A combination of static HTML pages and a content management system (also known as dynamic pages), can be done without a problem.
Many times, e-commerce sites will use a combination of such pages: static pages for the information and dynamic pages for product catalogs.
In addition, many static sites "add on" a content management system for blogs, or wikis. This is a good way to incorporate Web 2.0 features (such as interactivity) into an older site, without the need for a full redesign of the site.
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